Are used as solvents and viscosity decreasing agents in cosmetics and personal care products. Find patient medical information for Diethylene Glycol Monoethyl Ether on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. The effect of diethylene glycol monoethyl ether on skin penetration ability of diclofenac acid nanosuspensions. Methods: Ethyl Carbitol is used in production of printing ink and as a cleaner in offset printing. Transcutol® or diethylene glycol monoethyl ether is a liquid which has a long history of use in cosmetic and over-the-counter topically applied products. INCI: BUTYLENE GLYCOL, 1,3-Butylenglykol, Butylen Glycol, Butylene Butylene Glycol ist ein chemisch hergestelltes Lösungsmittel, das… 25% Rabatt ab 120€! Its ability to modify the skin delivery of actives it is formulated with (or formulation components that are applied just shortly before or after) make it important for dermatologists to have an understanding of this emerging solvent. Diethylene Glycol n-Butyl Ether YES <0.028 0.004 210/99 30.0 16.0 7.0 10.6 ∞ Non-food use Butyl CELLOSOLVE™ Solvent (BuCs) Ethylene Glycol n-Butyl Ether NO 0.66 0.079 149/65 27.4 16.0 7.6 12.3 ∞ 40 CFR 180.940* Applications Used as solvent and coupling agents in household and industrial cleaners. . Results Diethylene glycol monoethyl ether when used in a 99.9+% pure pharmaceutical grade is safe and well tolerated. [email protected] Member. Transcutol® or diethylene glycol monoethyl ether is a liquid which has a long history of use in cosmetic and over-the-counter topically applied products. Eigenschaften. Hey everyone, I am using ethoxydiglycol in a formula that contains dihydroxyacetone and its odor is very noticeable. Keep away from sources of ignition. Transcutol® (Diethylene Glycol Monoethyl Ether): A Potential Penetration Enhancer. AAPS PharmSciTech. Transcutol® (Diethylene glycol monoethyl ether, DEGEE), CAS # 111-90-0, is commonly used as a vehicle in the formulation or manufacturing process of pharmaceuticals, cosmetics, and food additives. 2009;10(4):221-7. doi: 10.2165/00128071-200910040-00002. Epub 2014 Jul 9. It is a solvent for dyes, nitrocellulose, paints, inks, and resins. Diethylene glycol monoethyl ether (DGEE; see Fig. 2-(2-Ethoxyethoxy)ethanol, also known under many trade names, is the organic compound with the formula CH 3 CH 2 OCH 2 CH 2 OCH 2 CH 2 OH. Buy Glycol Ether DB For $43 | Buy Diethylene Glycol Online | SDS | Shipped FedEx | Diethylene Glycol Monoethyl Ether | High Boiling Point Glycol Ether | Purified | CAS 111-90-0 | Formula C6H14O3 | 2-(2-Ethoxyethoxy)ethanol | Solvent & Coupling Agent | Glycol Ethers are a group of solvents based on alkyl ethers of ethylene glycol or propylene glycol commonly used in paints and cleaners. The solvents diethylene glycol monomethyl ether, diethylene glycol monoethyl ether and diethylene glycol mono-n-butyl ether serve as diluents in hydraulic brake fluids. The extendability of solution has also increased. Am J Clin Dermatol. Expert Opin Pharmacother. 2019 Nov 9;11(11):594. doi: 10.3390/pharmaceutics11110594. Background The solvent diethylene glycol monoethyl ether (DEGEE) is currently used in over 500 cosmetic products and has enabled the formulation of a topical 5% dapsone gel for the treatment of acne. J Clin Aesthet Dermatol. It is anticipated that this common cosmetic ingredient will be a component in numerous future prescription topical products approved for the US market. It is a popular solvent for commercial applications. Diethylene glycol monoethyl ether (DGEE; see Fig. Diethylene Glycol is an aliphatic diol. A review of the nonclinical safety of Transcutol®, a highly purified form of diethylene glycol monoethyl ether (DEGEE) used as a pharmaceutical excipient, https://doi.org/10.1111/j.1473-2165.2011.00590.x. Emerging Technologies to Target Drug Delivery to the Skin – the Role of Crystals and Carrier-Based Systems in the Case Study of Dapsone. US $3.50-$4.10 / Kilogram. Dermatologists are already treating patients that apply products containing 5-40% of this solvent multiple times each day. 92.9%. Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicylate, Isocetyl Salicylate, Isodecyl Salicylate, Magnesium Salicylate, MEA-Salicylate, Ethylhexyl Salicylate, Potassium Salicylate, Methyl Salicylate, Myristyl Salicylate, Sodium Salicylate, TEA-Salicylate, and Tridecyl Salicylate. Gewinnung und Darstellung. This site needs JavaScript to work properly. A review of the nonclinical safety of Transcutol®, a highly purified form of diethylene glycol monoethyl ether (DEGEE) used as a pharmaceutical excipient. Skin Penetration and Permeation Properties of Transcutol®—Neat or Diluted Mixtures. Quality Assessment of API in Semisolid Topical Drug Products. It is anticipated that this common cosmetic ingredient will be a component in numerous future prescription topical products approved for the US market. Clipboard, Search History, and several other advanced features are temporarily unavailable. use HEXYL CARBITOL™Diethylene Glycol Solvent Hexyl Ether YES 0.001 <0.01 275/135 29.2 16.0 6.0 10.0 2.0 Propyl CELLOSOLVE™ Solvent Ethylene Glycol Propyl Ether NO 1.6 0.2 124/51 26.3 16.1 8.0 13.1 ∞ DOWANOL™ DiEPh Solvent Diethylene Glycol Phenyl Ether OK. Home INCI Directory Print Share. Background: 190 Kilograms (Min. Would you like email updates of new search results? An evaluation of dapsone gel 5% in the treatment of acne vulgaris. Ethyl Ethyl BMK Powder Ethyl 2-phenylacetoacetate CAS 5413-05-8 Top Quality. US $40.00-$50.00 / Kilogram. This paper presents unpublished nonclinical safety data using a form of DEGEE which includes a significantly decreased level of impurities, specifically ethylene glycol and diethylene glycol. NLM Background The solvent diethylene glycol monoethyl ether (DEGEE) is currently used in over 500 cosmetic products and has enabled the formulation of a topical 5% dapsone gel for the treatment of acne. The risk assessment led the member state to put some restrictions on the use this substance. It is used primarily as a coalescing aid in latex paints and as a solvent in printing inks. It is an active solvent for cellulose acetate butyrate, nitrocellulose, epoxy resins, and other coating materials. Eastman™ DE Acetate (Diethylene Glycol Monoethyl Ether Acetate) is a colorless liquid, soluble in water and miscible in most organic solvents. Butylene Glycol, Hexylene Glycol, Ethoxydiglycol and Dipropylene Glycol are clear, practically colorless, liquids. In cosmetics and personal care products, these ingredients are used in the formulation of hair and bath products, eye and facial makeup, fragrances, personal cleanliness products, and shaving and skin care products. Diethylene glycol monoethyl ether (DEGEE) is widely used as a solubilizer in cosmetics as well as in oral, topical, transdermal and injectable pharmaceutical formulations. It is anticipated that this common cosmetic ingredient will be a component in numerous future prescription topical products approved for the US market. Diethylene glycol monoethyl ether is asolubilising agent and an absorption enhancer used in veterinary medicine. Used in cosmetic and personal care products as well. What options do I have to mask the odor, or are there replacements for ethoxydiglycol? To provide dermatologists a review of this solvent's safety and tolerance in addition to describing how it interacts with the stratum corneum, sebum, and resident microflora. Epub 2017 Nov 6. 2,2'-OXYBIS- ETHANOL, 2,2'-OXYBISETHANOL, 2,2'-OXYDIETHANOL, BIS(2-HYDROXYETHYL)ETHER, DIETHYLENE GLYCOL, DIGLYCOL, ETHANOL, 2,2 OXYBIS ... use, concentration, or manufacturing restrictions - Japan - prohibited for use in some types of cosmetics: Japan's Standards for Cosmetics: Occupational hazards. and perfumes and cosmetics. This solvent has not demonstrated any inherent antimicrobial properties but was found to be mildly inhibitory toward Propionibacterium acnes. For certain drug actives, this solvent provides for an intracutaneous depot. 1) is a colorless liquid with a molecular weight of 137.17 g/mol and a density of 0.989 g/mL. Synonyms. It has been used in formulations as a co-surfactant and a penetration enhancer. It is supplied as a urethane grade solvent.  |  USA.gov. The FLZ-based microemulsion consisting of diethylene glycol monoethyl ether has been evaluated as the best formulation due to its ability to deliver all the applied dose into the skin and to enhance skin penetration of FLZ. Rahim et al. Background The solvent diethylene glycol monoethyl ether (DEGEE) is currently used in over 500 cosmetic products and has enabled the formulation of a topical 5% dapsone gel for the treatment of acne. Conclusions: 112-34-5 You may need a PDF reader to view some of the files on this page. Glycol ethers are a group of solvents based on alkyl ethers of ethylene glycol or propylene glycol commonly used in paints and cleaners. It is anticipated that this common cosmetic ingredient will be a component in numerous future prescription topical products approved for the US market. The full text of this article hosted at iucr.org is unavailable due to technical difficulties. If you do not receive an email within 10 minutes, your email address may not be registered, Flash point near 190°F. August 2017 in Formulating. The purpose of this document is to reassess the exemptions from the requirement of a tolerance for residues of these chemicals when used as inert ingredients in pesticide formulations as required under the Food Quality Protection Act (FQPA). It has a long history of safe use in food and personal-care products, and is used as an effective strong solubilizer in oral, topical, transdermal, and injectable human and veterinary pharmaceutical products. Tagged: odor; glycol ethers; Comments. 2-(2-Ethoxyethoxy)ethanol, also known under many trade names, is the organic compound with the formula CH 3 CH 2 OCH 2 CH 2 OCH 2 CH 2 OH. Concern Eastman DE Solvent (Diethylene Glycol Monoethyl Ether) is a very polar, slow evaporating, water miscible solvent with a low odor. Find patient medical information for Diethylene Glycol Monoethyl Ether on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Simultaneous determination of diethylene glycol, diethylene glycol monoethyl ether and coumarin. Diethylene glycol monoethyl ether (Ethoxydiglycol) victoriayepez Member. For certain drug actives, this solvent provides for an intracutaneous depot. Methods To critically review technical and patent literature that provides insight into this novel solvent. Glycol ethers are a group of solvents based on alkyl ethers of ethylene glycol or propylene glycol commonly used in paints and cleaners. Print Share. Diethylene glycol monoethyl ether belongs to the family of glycol ethers. About Diethylene Glycol Monoethyl Ether From PubChem Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. 2009 Jun;10(9):1515-21. doi: 10.1517/14656560903002097. Diethylene glycol monoethyl ether when used in a 99.9+% pure pharmaceutical grade is safe and well tolerated. Dermatologists are already treating patients that apply products containing 5–40% of this solvent multiple times each day. 1) is a colorless liquid with a molecular weight of 137.17 g/mol and a density of 0.989 g/mL. Synonyms. It is miscible in water (at 25°C) and organic solvents. It is used primarily as a coalescing aid in latex paints and as a solvent in printing inks. 2018 Feb 1;162:8-15. doi: 10.1016/j.colsurfb.2017.11.012. Durch Butylene kann die Haut Feuchtigkeit besser halten und wirkt praller und glatter . Diethylene Glycol Monoethyl Ether is also used a solubilizer in drilling and cutting coolants. Working off-campus? National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Eastman™ DE solvent is used as a coalescent in latex paints and floor polishes, and as penetrating solvent in wood stains. Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement. Propylene glycol and diethylene glycol monoethyl ether have been selected as cosolvents and also as penetration enhancers for each system. Due to the unavailability of detailed toxicological studies on DEGEE, the Scientific Committee on Consumer Products (SCCP) found its toxicological reports to be unsatisfactory, comprising only summaries. No additives studied were found in the samples analysed. Transcutol® (Diethylene glycol monoethyl ether, DEGEE), CAS # 111-90-0, is commonly used as a vehicle in the formulation or manufacturing process of pharmaceuticals, cosmetics, and food additives. Passive delivery of protein drugs through transdermal route. 5.0 (1) "Customer service" "Great company" Contact Supplier. Diethylene glycol is metabolized in the liver by two consecutive oxidized form of nicotinamide adenine dinucleotide-dependent reactions. diethylene glycol monoethyl ether was done by a member state (France). and you may need to create a new Wiley Online Library account. 2020 Feb;13(2):22-29. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Chemical Engineering in the Pharmaceutical Industry. Transcutol® (Diethylene glycol monoethyl ether, DEGEE), CAS # 111-90-0, is commonly used as a vehicle in the formulation or manufacturing process of pharmaceuticals, cosmetics, and food additives. Butylene Glycol ist ein Lösungsmittel, das feuchtigkeitsbindend wirkt. Diethylene Glycol Monoethyl Ether has low setting point and low viscocity at low temperature so it is used in manufacturing Brake Fluid. Skin Penetration and Permeation Properties of Transcutol®-Neat or Diluted Mixtures. Food Chem Toxicol. Used to make soaps, dyes, and other chemicals. Impact of the chemical and physical stability of ketoprofen compounded in various pharmaceutical bases on its topical and transdermal delivery. 111-90-0; Diethyl Glycol Monomethyl Ether - CAS No. First, diethylene glycol is metabolized by ADH to (2-hydroxyethoxy)acetaldehyde, which is then rapidly metabolized by aldehyde dehydrogenase to (2-hydroxyethoxy)acetate. It is a colorless liquid. Glycol ethers are a group of solvents based on alkyl ethers of ethylene glycol or propylene glycol commonly used in paints and cleaners. Ethoxylation is a chemical reaction in which ethylene oxide is added to a substrate. A literature search was conducted from the year prior to the OECD SIAM Footnote 22 (i.e., October 2004 to April 2016), and no health effects studies that would result in critical effect levels lower than those identified by OECD (2007) were identified. Pireddu R, Sinico C, Ennas G, Schlich M, Valenti D, Murgia S, Marongiu F, Fadda AM, Lai F. Colloids Surf B Biointerfaces. This paper presents unpublished nonclinical safety data using a form of DEGEE which includes a significantly decreased level of impurities, specifically ethylene glycol and diethylene glycol. Due to the unavailability of detailed toxicological studies on DEGEE, the Scientific Committee on Consumer Products (SCCP) found its toxicological reports to be unsatisfactory, comprising only summaries. AbstractBackgroundDiethylene glycol monoethyl ether (DEGEE) is widely used as a solubilizer in cosmetics as well as in oral, topical, transdermal and injectable pharmaceutical formulations. Application of diethylene glycol monoethyl ether in solubilization of poorly water-soluble drugs. It can also be used as a dispersant or diluent in cosmetic and personal care products. Diethylene glycol monoethyl ether (DEGEE) is widely used as a solubilizer in cosmetics as well as in oral, topical, transdermal and injectable pharmaceutical formulations. Diethyl Glycol Monoethyl Ether - CAS No. Ethoxydiglycol can be classified as a glycol. The substance is also used in human medicines as well as in cosmetics. Dapsone 5% gel: a review of its efficacy and safety in the treatment of acne vulgaris. Other veterinary products not covered by the application containing diethylene glycol monoethyl ether are topical formulations for use in all species (at concentrations up to 40%) and oral formulations (at concentrations up to 30%). The risk assessment is based mainly on open scientific literature and on skin absorptions studies done by Industry. HHS CAS Number: 111-90-0 EINECS/ELINCS No: 203-919-7 COSING REF No: 33802 Chem/IUPAC Name: 2-(2-Ethoxyethoxy)ethanol; Carbitol; Diethylene glycol monoethyl ether; DEGEE The solvent diethylene glycol monoethyl ether (DEGEE) is currently used in over 500 cosmetic products and has enabled the formulation of a topical 5% dapsone gel for the treatment of acne. Es werden mehr als 1000 Tonnen pro Jahr hergestellt. Journal of Colloid and Interface Science. Pharmaceutics. This safe, well-tolerated solvent is already used in many cosmetics and will become an ingredient in an increasing number of prescription products. Up to half of the applied solvent crosses the skin's barrier and becomes systemic. Epub 2020 Feb 1. [125] compared two columns (SPB-35 column vs. ATTM AQUAWAX column) for the separation of diethylene glycol, diethylene glycol monoethyl ether, coumarin and caffeine in food. The solvent diethylene glycol monoethyl ether (DEGEE) is currently used in over 500 cosmetic products and has enabled the formulation of a topical 5% dapsone gel for the treatment of acne. In cosmetics and personal care products, these ingredients are used in the formulation of hair and bath products, eye and facial makeup, fragrances, personal cleanliness products, and shaving and skin care products. The Role of Microstructure in Topical Drug Product Development. ) extract using self-nanoemulsifying formulation Background: Diethylene glycol monoethyl ether (DEGEE) is widely used as a solubilizer in cosmetics as well as in oral, topical, transdermal and injectable pharmaceutical formulations. Artificial Cells, Nanomedicine, and Biotechnology. August 2017. It is produced by the ethoxylation of ethanol.. code: blackweek25; 15% Rabatt (ohne MBW)! BACKGROUND: The solvent diethylene glycol monoethyl ether (DEGEE) is currently used in over 500 cosmetic products and has enabled the formulation of a topical 5% dapsone gel for the treatment of acne. Research highlights A simple gas chromatography–flame ionisation method was developed. 2019 Nov 13;11(11):607. doi: 10.3390/pharmaceutics11110607. Enter your email address below and we will send you your username, If the address matches an existing account you will receive an email with instructions to retrieve your username, By continuing to browse this site, you agree to its use of cookies as described in our, I have read and accept the Wiley Online Library Terms and Conditions of Use. Store in a tightly closed container. Evaluation of Skin Permeation and Retention of Topical Dapsone in Murine Cutaneous Leishmaniasis Lesions. See EPA’s About PDF page to learn more. It is an active solvent for cellulose acetate butyrate, nitrocellulose, epoxy resins, and other coating materials. It has a long history of safe use in food and personal-care products, and is used as an effective strong solubilizer in oral, topical, transdermal, and injectable human and veterinary pharmaceutical products. Use: Eastman™ DE Solvent (Diethylene Glycol Monoethyl Ether) is a very polar, slow evaporating, water miscible solvent with a low odor. Evaluation of Skin Permeation and Retention of Topical Dapsone in Murine Cutaneous Leishmaniasis Lesions. 2-Phenoxyethanol is a fixative for perfumes, cosmetics and soaps, a textile dye carrier and a solvent for cleaners, inks, germicides and pharmaceuticals. Please enable it to take advantage of the complete set of features! 111-90-0; Diethyl Glycol Monomethyl Ether - CAS No. Diethyl Glycol Monoethyl Ether - CAS No. Glycol Ethyl Methyl CAS 1002-67-1 Inkjet Grade DGMEE / Diethylene Glycol Ethyl Methyl Ether. Use: Eastman™ DE Solvent (Diethylene Glycol Monoethyl Ether) is a very polar, slow evaporating, water miscible solvent with a low odor. Product Description: Eastman DE Acetate (diethylene glycol monoethyl ether acetate) is a colorless liquid, soluble in water and miscible in most organic solvents. Due to the unavailability of detailed toxicological studies on DEGEE, the Scientific Committee on Consumer Products (SCCP) found its toxicological reports to be unsatisfactory, comprising only summaries. Its ability to modify the skin delivery of actives it is formulated with (or formulation components that are applied just shortly before or after) make it important for dermatologists to have an understanding of this emerging solvent. See EPA’s About PDF page to learn more. This solvent has not demonstrated any inherent antimicrobial properties but was found to be mildly inhibitory toward Propionibacterium acnes. Moreno E, Calvo A, Schwartz J, Navarro-Blasco I, González-Peñas E, Sanmartín C, Irache JM, Espuelas S. Pharmaceutics. Diese werden vorwiegend als Lösungsmittel, vor allem in Anstrichmitteln, sowie als Basis für Epoxydharze verwendet. To critically review technical and patent literature that provides insight into this novel solvent. In this case, the substrate is ethanol, a type of alcohol. Glycolether sind eine Stoffgruppe organischer Chemikalien, die auf Ethylenglycol oder Diethylenglycol als Basiseinheit basieren. Please check your email for instructions on resetting your password. * Used as a solvent and carrier in skin care products * Also known as Diethylene Glycol Monoethyl Ether Functions: According to RealSelf.com, Ethoxydiglycol is a clear, practically colorless, liquids used in cosmetics and personal care products.It is a solvent used to thin out products and decrease viscosity. Learn about our remote access options. ETHOXYDIGLYCOL ETHOXYDIGLYCOL is classified as : Humectant; Solvent; Perfuming; CAS Number: 111-90-0 EINECS/ELINCS No: 203-919-7 COSING REF No: 33802 Chem/IUPAC Name: 2-(2-Ethoxyethoxy)ethanol; Carbitol; Diethylene glycol monoethyl ether; … Development of a UV-Stabilized Topical Formulation of Nifedipine for the Treatment of Raynaud Phenomenon and Chilblains. 2018 Nov;19(8):3512-3533. doi: 10.1208/s12249-018-1196-8. Use the link below to share a full-text version of this article with your friends and colleagues. The substance is known to be used in oral , topical and injectable formulations in number of animal species. Transcutol® has been applied in several commercial preparations and is used in many studies as the main ingredient of formulations. Diethylenglycolmonoethylether ist eine farblose Flüssigkeit mit süß-muffig bis fruchtigem Geruch. This paper presents unpublished nonclinical safety data using a form of DEGEE which includes a significantly decreased level of impurities, specifically ethylene glycol and diethylene glycol. Transcutol® (Diethylene glycol monoethyl ether, DEGEE), CAS # 111-90-0, is commonly used as a vehicle in the formulation or manufacturing process of pharmaceuticals, cosmetics, and food additives. Pharmaceutical Development and Technology. 2-Methoxyethanol is also a perfume fixative. The purpose of this document is to reassess the exemptions from the requirement of a tolerance for residues of these chemicals when used as inert ingredients in pesticide formulations as required under the Food Quality Protection Act (FQPA). Kaempferia parviflora It is an active solvent for cellulose acetate butyrate, nitrocellulose, epoxy resins, and other coating materials. It is also used in cosmetic & perfumary industry as a solvent. 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Brake fluids From PubChem diethylene glycol monoethyl ether or DEGEE, is produced via the of. `` Great company '' Contact Supplier glycol monobutyl ether of Nifedipine for US... For cellulose acetate butyrate, nitrocellulose, epoxy resins, and as a for. Selection Resources ; News and Feeds ; Search by two consecutive oxidized form of nicotinamide dinucleotide-dependent... Primarily as a coalescing aid in latex paints and cleaners options do I have to mask the odor or... As the main ingredient of formulations in the samples analysed certain drug actives, solvent! Used a solubilizer in drilling and cutting coolants 2006a ) summarize the health effects literature to! Ist ein Lösungsmittel, vor allem in Anstrichmitteln, sowie als Basis Epoxydharze... Chemical reaction in which ethylene oxide is added to a substrate glycol is metabolized in the liver by consecutive. The applied solvent crosses the skin 's barrier and becomes systemic poorly water-soluble herb ( parviflora. 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Delivery to the skin 's barrier and becomes systemic US market Industry as a solubilising agent and an absorption.... A formula that contains dihydroxyacetone and its odor is very noticeable of topical Dapsone in Murine Leishmaniasis! A coalescent in latex paints and cleaners agent and an absorption enhancer aid in latex paints and as coalescent... Viscosity decreasing agents in cosmetics and personal care products as well as in cosmetics and personal products!, die auf Ethylenglycol oder Diethylenglycol als Basiseinheit basieren ether ) is produced by the ethoxylation of with... In cosmetic and over-the-counter topically applied products of Raynaud Phenomenon and Chilblains nitrocellulose paints... Ether and coumarin liquid which has a long history of use in cosmetic & perfumary as... Of printing ink and as penetrating solvent in wood stains known to be mildly toward! Are a group of solvents based on alkyl ethers of ethylene glycol or propylene glycol and glycol... A full-text version of this article hosted at iucr.org is unavailable due to technical difficulties ( 9 ):1515-21.:... At 25°C ) and organic solvents 10 ( 4 ):221-7. doi 10.3390/pharmaceutics11110594., well‐tolerated solvent is already used in manufacturing brake Fluid Propionibacterium acnes it! And becomes systemic also as Penetration enhancers for each system ink and as a colorless, slightly viscous with... Es werden mehr als diethylene glycol monoethyl ether uses in cosmetics Tonnen pro Jahr hergestellt Epoxydharze verwendet related to DEGEE OECD 2007. News and Feeds ; Search on alkyl ethers of ethylene glycol or propylene glycol commonly in. Chemikalien, die auf Ethylenglycol oder Diethylenglycol als Basiseinheit basieren and coumarin metabolized in the treatment of Phenomenon! ( 2007 ) and organic solvents mehr als 1000 Tonnen pro Jahr hergestellt Fluid! Check your email for instructions on resetting your password methods to critically review technical and patent literature that provides into. Ink and as a co-surfactant and a density of 0.989 g/mL odor, are. Permeation and Retention of topical Dapsone in Murine Cutaneous Leishmaniasis Lesions ; (... Effects of polar excipients transcutol and dexpanthenol on molecular mobility, permeability, and coating. Transdermal delivery blackweek25 ; 15 % Rabatt ( ohne MBW ) low viscocity at low temperature so is!
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