propylene glycol monobutyl ether . Asthma/Respiratory . Sources/Uses. In our products, we use it as a cleaning agent that helps dissolve grease and soil from surfaces. Glycols & Glycol Ethers FBC offers a wide variety of Gycols and Gycol Ethers commonly used in cleaner and paint formulations. NLM 57018-52-7) in F344/N rats and B6C3F1 mice and a toxicology study of propylene glycol mono-t-butyl ether in male NBR rats (inhalation studies). Propylene glycol butyl ether, whose demand exceeded 400 kilo tons globally, held the largest market share in 2017. NIH Formulating with Glycol Ethers Article Substance name : Glycol Ether PNB CAS-No. Di(propylene glycol) butyl ether, mixture of isomers ≥98.5% Synonym: DOWANOL ® DPnB CAS Number 29911-28-2. The Panel added Propylene Glycol Butyl Ether to the list of ingredients included in the RR. PubMed:Solid absorbent collection and gas chromatographic determination of the propylene glycol butyl ether esters of 2,4,5-T in air. Registration dossier . It is used as a solvent and as a coalescent for water-borne latex coatings. Dipropylene Glycol Butyl Ether is supplied as a product that is >98.5% pure. Propylene glycol contains 3 carbon atoms, while butylene glycol is a little larger and contains 4 carbon atoms. Propylene Glycol N-Butyl Ether is a solvent that can be found in common household kitchen cleaners. 2004 Mar;(515):1-306. Let us know if there’s something you want, but don’t see listed. Propylene glycol mono-t-butyl ether (PGMBE) is used as a solvent in a variety of commercial applications. Butylene Glycol, Hexylene Glycol and Dipropylene Glycol are aliphatic diols that function as solvents and viscosity decreasing agents in cosmetics and personal care products. It has low water solubility and good coupling and demonstrates good solvency for coating resins. Global Propylene Glycol N Butyl Ether Market is expected to grow at a CAGR x.x% over the next ten years, and will reach at US$ XX.X Mn in 2029, from US$ XX.X Mn in 2019 email [email protected] phone +1 718 618 4351 (International) propylene glycol n-butyl ether . National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. We t studied the effects of propylene glycol mono-t-butyl ether on male and female rats and mice to identify potential toxic or cancer-related hazards to humans. KH Chemicals has a wide range of products and a large worldwide selling market. What’s so bad about PPG-14 butyl.  |  In summary, exposure to PGMBE resulted in nonneoplastic lesions of the kidney characteristic of alpha(2u)-globulin nephropathy, and may have increased renal tubular neoplasms in male rats. It is a mixture of four isomers. Evaluation of e-liquid toxicity using an open-source high-throughput screening assay. PubMed:Concentration and determination of the propylene glycol butyl ether esters of 2,4-dichlorophenoxyacetic acid (PGBE 2,4-D) in air. 2-methoxy-1-methylethyl acetate, 2propanol, 1methoxy, acetate, methoxyisopropyl acetate, propylene glycol methyl ether acetate, and propylene glycol monomethyl ether acetate Cancer Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments. Propylene glycol monobutyl ether, 1-Butoxy-2-propanol: Solvenon® DPnB: CAS: 29911-28-2 Dipropylene glycol monobutyl ether, Butoxy dipropanol (mixture of isomers) Solvenon® TPnB: CAS: 55934-93-5 Mixture of propylene glycol mono butyl ethers Propylene glycol tertiary‐butyl ether (PGTBE) also has been tested and fails to elicit these toxicities or birth defects in rats exposed by inhalation to substantial concentrations. In the 2-year study, male rats displayed exposure-related nonneoplastic lesions in the kidney, and may have shown marginal increases in tubular neoplasms. Occupational diseases associated with exposure to this agent: Industrial Processes with risk of exposure: Butoxypropanol; 1,2-Propylene glycol 1-monobutyl ether; 1-Butoxy-2-propanol; 2-Hydroxy-3-butoxypropane; Propasol solvent B; Propylene glycol monobutyl ether; n-Butoxy-2-propanol; n-Butoxypropanol; 1-Butoxypropan-2-ol; 2-Propanol, 1-butoxy-; [ChemIDplus] PnB; [Reference #1] Dowanol PNB glycol ether; [Dow Chemical MSDS] PGBE; [Glycol Ethers Online], Colorless liquid; [ICSC] Odor of ether; [Dow Chemical MSDS], Propylene series glycol ethers are used in surface coatings, leather, pesticides, electrical, industrial cleaners, resins, and printing inks; [ECETOC] Used as a coupling agent and solvent (degreasers, paint removers, metal cleaners, and hard surface cleaners), coalescent (latex coatings), coupling agent (water-based agricultural formulations), and chemical intermediate (epoxides, acid ester derivatives, solvents, and plasticizers); [Reference #1], Adverse effects in animal studies include adaptive liver changes and reversible CNS depression, but no hematological, genotoxic, or carcinogenic effects; [ToxPlanet: ECETOC] A skin and eye irritant; [ICSC] May cause moderate skin and eye irritation; May cause mild, reversible corneal injury; [Dow Chemical MSDS] See "Dipropylene glycol n-butyl ether.". In the liver, the incidences of hepatocellular adenomas occurred with a positive trend in male rats, and may have been related to PGMBE exposure. Another name for it is “propane-1,2-diol,” which is sometimes used when listing it as a compound on ingredient labels. Butyl Polyoxyalkylene Ethers (new data only) – Dec 2016 – Monice Fiume Reported Use - … used as a PENETRATION enhancer. P-Series glycol ethers are propylene oxide-based, more hydrophobic, have lower surface tension and lower toxicity, and work well in higher pH systems. Propylene glycol mono--butyl ether is used as a solvent in all-purpose cleaners, inks, and nail polish lacquers. Meeting report: summary of IARC monographs on formaldehyde, 2-butoxyethanol, and 1-tert-butoxy-2-propanol. Propylene glycol mono-t-butyl ether (PGMBE) is used as a solvent in a variety of commercial applications. Dipropylene Glycol Butyl Ether is manufactured by reacting Propylene Oxide with Butanol. Cancer: 06/11/2004. Is hypersensitivity pneumonitis work-related? Propylene Glycol N-propyl Ether Propylene glycol N-propyl ether (PnP) is a colorless liquid with an ether-like odor. Ethyl tertiary-butyl ether: a toxicological review. The properties of Arcosolv PNB support its use in agricultural, coating, cleaning, ink, textile and adhesive products.  |  Male and female F344/N rats and B6C3F(1) mice were exposed to PGMBE by whole-body inhalation for 2 or 14 weeks (0, 75, 150, 300, 600, or 1200 ppm) or 2 years (0, 75, 300, or 1200 ppm); male NBR rats were exposed for 2 weeks. OBJECTIVES: The increased use of glycol ethers (GEs) for water-based paints and cleaning products, combined with a lack of information about many of these products, particularly with regard to the effects of percutaneous exposure, led us to evaluate the skin absorption rates of a group of glycol ethers in vitro.METHODS: Skin permeation was calculated using the Franz cell method with human skin. Recommended use and restrictions on use Use of the substance/mixture : Solvent 1.3. NTP technical report on the toxicology and carcinogenesis studies of propylene glycol mono-t-butyl ether (CAS No. The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. Dipropylene Glycol Butyl Ether is the propylene oxide-based glycol ether. It is so toxic, and penetrates so quickly that. We t studied the effects of propylene glycol mono-t-butyl ether on male and female rats and mice to identify potential toxic or cancer-related hazards to humans. Developmental & Reproductive Toxicity . Glycols are rarely found in nature but the simple structure especially of propylene glycols (i.e. About 2% of these are Alcohol & Hydroxybenzene & Ether. PnP Glycol Ether Propylene Glycol n-Propyl Ether NO 1.5 0.21 118/48 25.4 15.3 4.9 11.2 ∞ Applications Air fresheners and fragrances, cleaner formulations such as glass cleaners, hard surface cleaners, floor cleaners, rust removers, industrial cleaners, and metal cleaners DOWANOL™ TPnB Glycol Ether Tripropylene Glycol n-Butyl Ether Continuing changes in E-series glycol ether products: In the major regions of the world, growth has been primarily for the butyl products (and some smaller-volume specialty glycol ethers); the methyl and ethyl products groups have been in decline. It is majorly used in products that are used in treating metal and non-metal surfaces, laboratory products, and in water treatment formulation. Renal lesions suggestive of alpha(2u)-globulin nephropathy were observed in male F344/N, in the 2 and 14-week studies, no kidney lesions were seen in NBR rats. Would you like email updates of new search results? eCollection 2018 Mar. This site needs JavaScript to work properly. 2009 Feb;53(1):6-15. doi: 10.1016/j.yrtph.2008.09.005. The EPA requires The category contains four structurally related propylene glycol ethers: Propylene Glycol n-Butyl Ether (PnB, 5131-66-8, ma jor (“alpha”) isomer, 29387-86-8 isomeric mixture) Dipropylene Glycol n-Butyl Ether (DPnB, 29911-28-2 major isomer or 35884-42-5 isomeric mixture)) Propylene glycol tertiary ‐butyl ether (PGTBE) also has been tested and fails to cause these toxicities or birth defects in rats exposed by inhalation to substantial concentrations. those who handle it must wear face masks, gloves and goggles. Propylene Glycol N-Butyl Ether Definition. NACRES NA.23 doi: 10.1371/journal.pbio.2003904. These solvents are widely used paints & coatings, industrial cleaners, and inks. (NTP, 1992). 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